Ahead of this weekend’s Serie A kick-off, Football Italia looks at the crucial fixtures for the top sides, starting with champions Juventus.
The Bianconeri have won the Scudetto for the past six seasons in a row, breaking their own record and that of il Grande Torino.
Unsurprisingly Massimiliano Allegri’s side start as favourites this season, but there have been worrying signs over the summer.
Leonardo Bonucci and Dani Alves have both left the club, while Juve still look short in midfield.
Add in the Supercoppa Italiana defeat to Lazio, and the Old Lady could have a serious challenge for her crown this season.
Here are five fixtures which could define Juventus’ season.
Milan-Juventus [Week 11]
Big-spending Milan look set to challenge the Bianconeri for the Scudetto this season, and the two meet for the first time just before Halloween.
Leonardo Bonucci will line up against his former side for the first time after his shock €40m transfer this summer.
By this point we’ll have had 10 games of the league season, and should have an idea of the runners and riders in the title fight.
If, as expected, both sides are in the mix we could be in for a real firecracker atmosphere at San Siro.
Napoli-Juventus [Week 15]
Napoli have pushed the Old Lady close in the past two seasons, and have kept their squad together this summer.
Gonzalo Higuain returning to Naples will always be an event after his controversial transfer last summer, but this could be a big opportunity to put down a Scudetto marker for the Partenopei.
Maurizio Sarri’s side have a poor record in Turin, but claimed a 1-1 draw at the San Paolo in Serie A last season, as well as winning 3-2 in the Coppa Italia semi-final.
Juventus-Inter [Week 16]
December is shaping up to be a defining month for Max Allegri and his side, with Inter visiting Turin just a week after the Napoli game.
Luciano Spalletti took his Roma side to second last season, and they beat a heavily rotated Bianconeri 3-1 in Week 36.
Now on the Nerazzurri bench, the Coach will be hoping to achieve a similar feat in his first Derby d’Italia.
Juventus-Napoli [Week 34]
The return leg with Napoli would be a big game anyway, but it's the calendar which could really pile the pressure on Juve in late April.
The Bianconeri have designs on the Champions League, and the semi-final first legs will be played on April 24 and 25.
Napoli visit Turin prior to those games - though of course the Partenopei could be involved in the Champions League too - and the weekend after brings a trip to Inter.
Juventus will hope to still be in the hunt for three trophies at this point in the season, but if they are they’ll have a truly difficult end to the month.
Roma-Juventus [Week 37]
The penultimate weekend of the season sees the Old Lady face another potential Scudetto rival, in a fixture they’ve lost in the past two Serie A campaigns.
The Giallorossi could still be in the hunt for the title, and if not any dropped points could let another rival in.
Juve have won the Coppa Italia for the past three seasons, and the cup final will be played in the midweek before they face the Giallorossi.