Milan give Leonardo Bonucci his competitive debut with Andre Silva leading the attack in their Europa League play-off with Shkendija.
It kicks off at San Siro at 19.45 UK time (18.45 GMT), you can follow the build-up and action on the LIVEBLOG.
The Rossoneri already got through one preliminary round, beating Craiova 3-0 on aggregate, and have further reinforced their squad.
Bonucci was unavailable for that tie, but is ready for his competitive debut this evening and does it with the captain’s armband.
Lucas Biglia and Alessio Romagnoli are injured, while Coach Vincenzo Montella left out M’Baye Niang, Gabriel Paletta, Davide Calabria, Jose Sosa and Gustavo Gomez.
Milan have their Serie A opener against Crotone on Sunday evening, so Montella makes a few changes to keep the squad fresh.
Andre Silva leads the attack, flanked by Fabio Borini and Suso, while Andrea Conti takes the right-back role.
Franck Kessie and Hakan Calhanoglu surround Riccardo Montolivo in midfield.
Shkendija field a 4-2-3-1 system with Besart Ibraimi as the lone centre-forward, supported by Marjan Radeski, Feran Hasani and Besart Abdurahimi.
Milan: G Donnarumma; Conti, Bonucci, Zapata, Antonelli; Kessie, Montolivo, Calhanoglu; Borini, Andre Silva, Suso
Milan bench: Storari, Bonaventura, Abate, Musacchio, Cutrone, Rodriguez, Locatelli
Shkendija: Zahov; Todorovski, Bejtulai, Cuculi, Celikovic; Alimi, Totre; Radeski, Hasani, Abdurahimi; Ibraimi
Shkendija bench: Avdyli, Murati, Zejnulai, Bojku, Teqja, Fazlagikji, Shefiti