Alessandro Florenzi and Radja Nainggolan return to the starting XI, as Roma host troubled Udinese and push to close on the leaders.
It kicks off at 14.00 UK time (13.00 GMT), follow the build-up and action from all today’s Serie A games on the LIVEBLOG.
The Giallorossi are finding their feet and confidence under new Coach Eusebio Di Francesco after holding Atletico Madrid to a stalemate, then crushing Verona and Benevento.
Patrik Schick is still on the treatment table with Emerson Palmieri and Rick Karsdorp, but Florenzi is in the starting XI again at right-back.
Nainggolan also returns after he was rested due to a slight muscular problem, partnering Daniele De Rossi and Kevin Strootman.
Stephan El Shaarawy gets the nod in attack with Edin Dzeko and Diego Perotti.
Udinese are in trouble, losing four of their five Serie A games this season and with Coach Gigi Del Neri increasingly under pressure.
He has to do without captain Danilo, who sustained a potentially serious injury in training yesterday, Silvan Widmer and Stipe Perica.
Kevin Lasagna and Maxi Lopez lead the way with support from Rodrigo De Paul and Jakub Jankto.
Gabriele Angella has to take over in defence from Danilo, but Seko Fofana is not fully fit, so Antonin Barak is a late replacement in midfield.
The big change is that young goalkeeper Simone Scuffet is dropped in favour of the more experienced Albano Bizzarri.
Roma have won each of their last eight meetings with Udinese, home and away. The Friulani picked up just one point since their last victory, 3-2 at the Olimpico in October 2012.
Roma: Alisson; Florenzi, Manolas, Fazio, Kolarov; Strootman, De Rossi, Nainggolan; Perotti, Dzeko, El Shaarawy
Udinese: Bizzarri; Stryger Larsen, Angella, Nuytinck, Samir; De Paul, Barak, Behrami, Jankto; Maxi Lopez, Lasagna