Radja Nainggolan and Ciro Immobile both pass late fitness tests and will start the Derby della Capitale between rivals Roma and Lazio.
It kicks off at the Stadio Olimpico at 17.00 GMT, follow the build-up and action from this game and Napoli–Milan on the LIVEBLOG.
The Capital clubs are on a fairly even keel so far this season, both equally impressive in Serie A and Europe, despite not spending anywhere near as much as other clubs.
Radja Nainggolan and Ciro Immobile both pass late fitness tests and will start the Derby della Capitale between rivals Roma and Lazio.
It kicks off at the Stadio Olimpico at 17.00 GMT, follow the build-up and action from this game and Napoli-Milan on the LIVEBLOG.
The Capital clubs are on a fairly even keel so far this season, both equally impressive in Serie A and Europe, despite not spending anywhere near as much as other clubs.
New Coach Eusebio Di Francesco has brought his 4-3-3 pressing style to Roma and they’ve run with it, even when regularly rotating the squad.
Patrik Schick and Rick Karsdorp are out of action, with Emerson Palmieri on the road to recovery from his torn ACL in May.
There were major doubts over Nainggolan, who interrupted international duty with Belgium due to a groin problem, but he will grit his teeth and start the match with Kevin Strootman and Daniele De Rossi.
Edin Dzeko is seeking to end his five-match goal drought, surrounded by Diego Perotti and Stephan El Shaarawy.
Lazio had a fitness issue of their own, as Immobile returned from Italy’s World Cup play-off disaster with a knock, but he too is pushing on to be there in this huge fixture.
He’s sorely needed, as Simone Inzaghi cannot count on Felipe Anderson, Felipe Caicedo, David Di Gennaro or Wallace.
Luis Alberto and Sergej Milinkovic-Savic provide support for the current Capocannoniere.
Lazio are on a run of nine consecutive victories between Serie A and the Europa League, but have lost four of their last League five meetings with Roma.
They also knocked the Giallorossi out of the Coppa Italia semi-final, 4-3 on aggregate.
Roma: Alisson; Florenzi, Manolas, Fazio, Kolarov; De Rossi, Strootman, Nainggolan; El Shaarawy, Perotti, Dzeko
Roma bench: Lobont, Skorupski, J.Jesus, B.Peres, Emerson, Moreno, Castan, Pellegrini, Gerson, Gonalons, Under.
Lazio: Strakosha; Bastos, De Vrji, Radu; Marusic, Parolo, Leiva, Milinkovic-Savic, Lulic; Luis Alberto; Immobile
Lazio bench: Vargic, Guerrieri, Mauricio, Patric, Basta, Luis Felipe, Lukaku, Jordao, Murgia, Nani, Palombi, Neto
Ref: Rocchi