Alessandro Del Piero and Mirko Vucinic take on Zlatan Ibrahimovic and Stephan El Shaarawy in the Coppa Italia semi-final tonight.
The Bianconeri won the first leg 2-1 at San Siro, so the pressure is on the Rossoneri to turn that result around with their own away goals.
Antonio Conte has rested Alessandro Matri and Gigi Buffon, while Andrea Barzagli is injured.
He adopts the 4-3-3 system with a largely first choice defence, Andrea Pirlo facing his former teammates flanked by Emanuele Giaccherini and Arturo Vidal in midfield.
Del Piero gets a rare start alongside Vucinic and Simone Pepe. Martin Caceres scored both goals in the first leg, but is on the bench tonight.
Milan’s injury list is extensive and includes Alessandro Nesta, Robinho, Alexandre Pato, Kevin-Prince Boateng, Ignazio Abate, Mark Van Bommel, Alexander Merkel, Rodney Strasser, Antonio Cassano and Mathieu Flamini.
There were doubts over whether Ibrahimovic could feature at all, as he has been suffering from flu symptoms, but he is in the starting XI.
Alberto Aquilani starts against his former club, while Clarence Seedorf returns from injury as support for Urby Emanuelson and Stephan El Shaarawy.
Juventus: Storari; Lichtsteiner, Bonucci, Chiellini, De Ceglie; Giaccherini, Pirlo, Vidal; Pepe, Del Piero, Vucinic
Juventus bench: Manninger, Caceres, Estigarribia, Marchisio, Padoin, Quagliarella, Borriello
Milan: Amelia; Antonini, Mexes, Thiago Silva, Mesbah; Aquilani, Seedorf, Muntari; Emanuelson; Ibrahimovic, El Shaarawy
Milan bench: Abbiati, Yepes, Bonera, Nocerino, Gattuso, Maxi Lopez, Inzaghi