Milan have Zlatan Ibrahimovic, Kevin-Prince Boateng and Robinho against Leo Messi and Alexis Sanchez’s Barcelona in tonight’s Champions League quarter-final.
The first leg kicks off at San Siro at 19.45 UK time and Massimiliano Allegri has to deal with a never-ending injury crisis.
Thiago Silva was the latest addition to the absentee list with Ignazio Abate, Alexandre Pato, Alexander Merkel, Gennaro Gattuso, Antonio Cassano and Pippo Inzaghi.
Mark van Bommel is also suspended in midfield, so there are changes for this game.
Alessandro Nesta and Robinho are back in the starting XI after several weeks on the treatment table, while Boateng made his comeback as a substitute in the 2-1 win over Roma on Saturday.
Ibrahimovic faces his former club, but this is the third time this season the two teams have come face to face, as there was a 2-2 draw at the Camp Nou and 3-2 Barcelona victory in Milan during the group phase.
Barcelona are the reigning European and World champions, coming off seven consecutive Liga victories.
Dani Alves returns from a ban, but David Silva and Eric Abidal are out for the rest of the season, while Ibrahim Afellay and Andreu Fontas are also long-term absentees.
Thiago Alcantara returned from a right shin injury and is on the bench, but Adriano has a thigh problem.
Former Udinese talent Alexis Sanchez partners Messi in attack.
Milan: Abbiati; Bonera, Nesta, Mexes, Antonini; Nocerino, Ambrosini, Seedorf; Boateng; Robinho, Ibrahimovic
Milan bench: Amelia, Mesbah, Yepes, Aquilani, Emanuelson, Maxi Lopez, El Shaarawy
Barcelona: Victor Valdes; Daniel Alves, Piqué, Mascherano, Puyol; Xavi Hernandez, Busquets, Keita, Iniesta; Messi; Alexis Sanchez
Barcelona bench: Jose Pinto, Marc Muniesa, Montoya, Fabregas, Thiago Alcantara, Pedro Rodriguez, Tello
Betting on Serie A? Bet365 are offering a 100% deposit bonus, up to £200 - find out more