Italy called up numerous young players for the friendly against England, so Under-21 Coach Devis Mangia had to readjust his squad for Holland.
Cesare Prandelli is focusing on the next generation for Wednesday’s high-profile game with Roy Hodgson’s side in Berne.
This includes many Azzurrini starlets such as Stephan El Shaarawy, Manolo Gabbiadini and Mattia De Sciglio.
Also called up is Pescara goalkeeper Mattia Perin, while Chievo striker Alberto Paloschi has had to pull out of the Under-21 side due to an ankle injury.
Coach Mangia has called in Sassuolo goalkeeper Mirko Pigliacelli, Cesena left-back Alessandro Favalli and Grosseto defender Marco Crimi.
The Azzurrini face Holland in Leeuwarden on Wednesday in a friendly that kicks off at 16.30 UK time.
Italy Under-21 squad to face Holland:
Goalkeepers:Francesco Bardi (Novara), Simone Colombi (Modena), Mirko Pigliacelli (Sassuolo)
Defenders:Luca Caldirola (Cesena), Marco Capuano (Pescara), Alessandro Crescenzi (Pescara), Giulio Donati (Inter), Paolo Frascatore (Sassuolo), Alberto Masi (Juventus), Simone Romagnoli (Pescara), Mario Sampirisi (Genoa), Alessandro Favalli (Cesena), Marco Crimi (Grosseto)
Midfielders:Alessandro Florenzi (Roma), Lorenzo Insigne (Napoli), Karim Laribi (Sassuolo), Luca Marrone (Juventus), Fausto Rossi (Juventus), Jacopo Sala (Hamburg), Riccardo Saponara (Empoli), Federico Viviani (Padova)
Strikers:Giuseppe De Luca (Varese), Ciro Immobile (Genoa), Samuele Longo (Inter)
Betting on Serie A? Bet365 are offering a 100% deposit bonus, up to £200 - find out more