Napoli give teenage star Lorenzo Insigne his first Serie A start alongside Edinson Cavani in their visit to Palermo.
The Serie A season kicks off for the Partenopei in Sicily this evening at 19.45 UK time.
Goran Pandev, Andrea Dossena and Juan Camilo Zuniga all sit out bans earned during the contentious Italian Super Cup defeat to Juventus in Beijing.
This gives Italian Under-21 international Insigne his big chance to start with Cavani with Marek Hamsik in his new deeper role.
Palermo have new Coach Giuseppe Sannino in charge, but Jasmin Kurtic and Carlos Labrin are suspended with Lores Varela, Eran Zahavi and Andrea Mantovani injured.
New buy Paulo Dybala’s international transfer has not yet arrived, so he’ll have to wait for his Serie A debut.
Instead, captain Fabrizio Miccoli is partnered by Abel Hernandez, while Steven Von Bergen makes his first Palermo appearance in defence.
Palermo: Ujkani; Cetto, Von Bergen, Munoz; Pisano, Barreto, Donati, Brienza, Bertolo; Hernandez, Miccoli
Napoli: De Sanctis; Campagnaro, Cannavaro, Britos; Maggio, Behrami, Inler, Hamsik, Aronica; Insigne, Cavani
Betting on Serie A? Bet365 are offering a 100% deposit bonus, up to £200 - find out more