Zdenek Zeman has named his 21-man squad for the trip to Inter, as Mattia Destro is set to make his Serie A Roma debut.
The Giallorossi travel to San Siro on Sunday, kick-off at 19.45 UK time.
Destro missed the opening 2-2 draw with Catania due to a ban, but is back in the squad and ready to face Andrea Stramaccioni’s side.
Panagiotis Tachtsidis is also included after recovering from an injury, but Michael Bradley and Dodo are still sidelined.
Roma squad for Inter: 1 Lobont, 3 Marquinhos, 5 Castan, 7 Marquinho, 8 Lamela, 9 Osvaldo, 10 Totti, 11 Taddei, 15 Pjanic, 16 De Rossi, 17 Lopez, 22 Destro, 23 Piris, 24 Stekelenburg, 26 Tallo, 29 Burdisso, 42 Balzaretti, 46 Romagnoli, 48 Florenzi, 55 Svedkauskas, 77 Tachtsidis
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £5,000 monthly.