The Milan duo of Kevin Prince Boateng and Riccardo Montolivo are set for a spell on the sidelines, the club have confirmed.
The No 10 will be out for about two weeks after he underwent surgery on his right hand earlier on Monday.
Montolivo, meanwhile, could be missing for up to 21 days after he sustained a right thigh strain in the win over Bologna at the weekend.
Betting on Serie A? Bet365 are offering a 100% deposit bonus, up to £200 - find out more