Chievo Coach Eugenio Corini makes changes on his debut, introducing Adrian Stoian in a trequartista role, as Maxi Lopez returns for Sampdoria.
The 17.00 BST kick-off is at the Stadio Bentegodi and you can watch this and other Serie A games LIVE on your computer.
The match comes just days after Domenico Di Carlo was fired following five consecutive defeats, bringing in ex-Flying Donkeys captain Corini to take over.
Sergio Pellissier is out due to a spell in hospital to have kidney stones removed, while Marco Rigoni, Luciano and Alberto Paloschi are also injured.
Corini picks Stoian for a rare start in support of Cyril Thereau and David Di Michele.
Sampdoria stick with their tried and tested 4-3-3 system, but are without injured forwards Nicola Pozzi and Eder.
Maxi Lopez returns from his two-match ban and is joined in the trident by Marcelo Estigarribia and Nenad Krsticic.
Andrea Poli and Juan Antonio are also sidelined with Daniele Gastaldello suspended, but Enzo Maresca is back in the starting XI.
Chievo: Sorrentino; Sardo, Dainelli, Cesar, Dramè; Guana, L Rigoni, Hetemaj; Stoian, Thereau; Di Michele
Sampdoria: Romero; Berardi, Rossini, Costa, Poulsen; Munari, Maresca, Obiang; Estigarribia, Maxi Lopez, Krsticic