Juventus boss Antonio Conte may rest a host of first team regulars in the game against Pescara this weekend.
According to the Gazzetta dello Sport, the tactician will ponder giving as many as five players a break ahead of the trio of ties versus Lazio, Chelsea and Milan.
Andrea Barzagli, Leonardo Bonucci, Andrea Pirlo, Kwadwo Asamoah and Sebastian Giovinco could all be allowed to catch their breath.
In attack, Mirko Vucinic is expected to return to the starting line-up. He may be partnered in attack by Fabio Quagliarella.
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £5,000 monthly.