Roma hot-shot Pablo Daniel Osvaldo took no part in training on Friday because of illness.
The 26-year-old, who has scored seven goals in just nine League games this term, missed the morning session with a gastrointestinal problem.
It is unclear at this stage whether he will recover in time for Sunday’s Serie A test at Pescara.
His absence would seemingly give Mattia Destro a chance in the first team after spending time on the bench recently.
The Giallorossi are already without top scorer Erik Lamela for the Stadio Adriatico trip because of an ankle issue.