Lazio and Catania go head-to-head this evening for a place in the Coppa Italia Semi-Final and Vladimir Petkovic goes for a three-man defence.
The one-off Quarter-Final kicks off at the Stadio Olimpico in Rome at 20.00 GMT.
Vladimir Petkovic changes to a 3-5-1-1 system with several changes to his usual starting XI.
Sergio Floccari gets the opportunity to shine in attack with Lorik Cana used in a centre-back role, while Antonio Candreva is in the ‘hole.’
The Biancocelesti have already experimented with three at the back in the Europa League and Coppa Italia.
Catania stick to their traditional 4-3-3 system and practically a full-strength side.
The Sicilians can count on creative midfielder Francesco Lodi, who must sit out a three-match Serie A ban, but is available for the Coppa Italia.
Lazio:Bizzarri; Biava, Cana, Radu; Cavanda, Gonzalez, Ledesma, Hernanes, Lulic; Candreva; Floccari
Catania: Frison; Bellusci, Legrottaglie, Rolin, Capuano; Izco, Lodi, Almiron; Gomez, Bergessio, Barrientos
Betting on Serie A? Bet365 are offering a 100% deposit bonus, up to £200 - find out more