Week 26 brings the huge Milan Derby, Napoli’s trip to Udinese, Juventus face giant-killers Siena and this evening a battle for safety between Palermo and Genoa.
The revived Roma look to increase Atalanta’s problems, Fiorentina face a Dall’Ara test and Lazio want to put last week’s upset behind them against Pescara.
It’s a potentially tricky weekend for the leaders, as Juventus welcome Siena fresh from beating Inter and Lazio.
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £5,000 monthly.