Lazio will start with Sergio Floccari as the lone front-man when they face Pescara at Stadio Olimpico this evening.
The 31-year-old will play up front in place of the injured Miroslav Klose, whilst new signing Louis Saha remains on the bench.
For Pescara meanwhile, they drop young goalkeeper Mattia Perin in favour of Ivan Pelizzoli.
Lazio: Marchetti; Konko, Cana, Dias, Radu; Candreva, Gonzalez, Ledesma, Hernanes, Lulic; Floccari
Pescara: Pelizzoli; Balzano, Cosic, Bocchetti, Capuano, Zauri; Rizzo, Cascione, Bjarnason; Abbruscato, Celik
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's World Cup tipster competition - £10,000 to be won!