Inter go to Catania without Antonio Cassano in a battle for Europe, while Roma aim to end Genoa’s revival this evening.
Click here for all the individual match previews, including reports from Napoli-Juventus and Milan-Lazio.
The action starts at 11.30am GMT when Torino welcome Palermo, who have Gian Piero Gasperini back on the bench a month after he was sacked.
There are also relegation dogfights in Pescara, Siena and Bologna, while Fiorentina need to prove themselves against Chievo.
Tickets for the Champions League final between Juventus and Real Madrid are still on sale with reseller Viagogo - Click to find out more