Only two points separate Lazio and Catania in today’s head-to-head for Europe, as the Biancocelesti try to end their run of three consecutive defeats with Louis Saha.
It kicks off at the Stadio Olimpico at 14.00 GMT, click here for a match preview.
The Elefantini are the surprise package of the campaign and have a strong record here, undefeated since November 2008, then beating Lazio 4-0 earlier this season.
Hernanes returns from suspension, but Michael Ciani sits out a ban with Bruno Pereirinha, Sergio Floccari, Abdoulay Konko, Andre Dias and Cristian Brocchi injured.
Miroslav Klose is back on the bench after a two-month lay-off, so January signing Saha gets his first start in a Lazio jersey.
Giuseppe Biava had been expected to miss out, but is instead risked in the three-man defence.
Catania duo Nicolas Spolli and Alessandro Potenza are suspended with Sergio Almiron sidelined.
The first choice front three of Pablo Barrientos, Alejandro Gomez and Gonzalo Bergessio are reunited.
Lazio: Marchetti; Biava, Cana, Radu; Gonzalez, Onazi, Ledesma, Hernanes, Lulic; Candreva; Saha
Catania: Andujar; Alvarez, Legrottaglie, Bellusci, Marchese; Izco, Lodi, Biagianti; Barrientos, Bergessio, Gomez