Juventus field a completely revamped side for today’s early kick-off against bottom of the table Pescara, but Mirko Vucinic partners Sebastian Giovinco.
The Serie A Week 31 tie starts in Turin at 17.00 UK time (16.00 GMT). Click here for a match preview.
The Bianconeri want to put the Scudetto under lock and key, but were also shaken by their 2-0 Champions League quarter-final defeat to Bayern Munich.
Coach Antonio Conte is forced into numerous changes, as Gigi Buffon is suffering from flu symptoms and sits on the bench in favour of Marco Storari.
Giorgio Chiellini and Andrea Barzagli are both suspended, making way for Luca Marrone, while Andrea Pirlo and Claudio Marchisio are rested.
Nicolas Anelka had been expected to start today, but is not even in the squad, as he is away on personal leave to deal with a family matter.
Mauricio Isla, Martin Caceres, Nicklas Bendtner and Simone Pepe are all injured.
Arturo Vidal and Stephan Lichtsteiner start, as they are suspended for the second leg against Bayern Munich on Wednesday.
Pescara are propping up the Serie A table thanks to one point from the last 11 rounds and are on their third Coach of the campaign.
Giovanni Stroppa resigned, then last month Cristiano Bergodi was sacked to promote Cristian Bucchi from the Primavera youth team job.
Mervan Celik sits out a ban, joining the injured Vladimir Weiss, Antonio Balzano, Antonio Bocchetti, Gaetano D’Agostino, Ante Vukusic, Luciano Zauri and Uros Cosic.
Juan Fernando Quintero, who has been linked to Juventus among other clubs, starts in a supporting trident behind striker Ferdinando Sforzini.
Juventus: Storari; Bonucci, Marrone, Peluso; Lichtsteiner, Vidal, Pogba, Giaccherini, Asamoah; Vucinic, Giovinco
Pescara: Pelizzoli; Zanon, Kroldrup, Capuano, Modesto; Rizzo, Togni; Caprari, Quintero, Sculli; Sforzini
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £5,000 monthly.