Inter and Lazio have had more than their fair share of problems, so go head-to-head in a battle for Europe.
Only two points separate these teams going into San Siro with kick-off at 19.45 UK time. Click here for a match preview.
The Biancocelesti stopped the rot with Sunday’s 6-0 victory over Bologna, in which Miroslav Klose became the first Serie A player since 1986 to score five in a single game.
Ederson, Stefano Mauri and Cristian Brocchi are unavailable, but Klose leads the attack with support from Sergio Floccari.
Inter have lost six of the last eight rounds and are just desperate for the season to end, as they risk missing out on Europe altogether.
Tommaso Rocchi returns to face his former club, but the injury crisis includes the likes of Javier Zanetti, Rodrigo Palacio, Diego Milito, Antonio Cassano, Walter Gargano and Walter Samuel.
If they are going to win any game, it should be this one, as Lazio haven’t conquered San Siro in Serie A since 1998 and lost their last seven consecutive visits.
Inter: Handanovic; Jonathan, Ranocchia, Juan Jesus, Pereira; Kuzmanovic, Kovacic, Cambiasso; Guarin; Alvarez, Rocchi
Lazio: Marchetti; Konko, Dias, Cana, Radu; Candreva, Ledesma, Hernanes, Lulic; Floccari, Klose
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £11,000 to be won monthly!