Fiorentina look to Mario Gomez, Giuseppe Rossi and Juan Cuadrado in their Europa League play-off with Grasshopper.
The first leg kicks off in Zurich at 20.00 UK time (19.00 GMT) for entry into the competition proper.
The Viola are without David Pizarro after he picked up a thigh injury on international duty.
Adem Ljajic is on the bench due to the ‘tension’ of his on-going contract saga, joined by Joaquin.
Ex-Bayern Munich star Gomez leads the way just months after lifting the Champions League trophy, while Rossi is given his first competitive start in two years.
There were question marks over who would be chosen in goal and Neto got the nod ahead of Munua.
Grasshopper won the Swiss Cup last season and have Anatole Ngamukol as their main threat in attack.
Caio and Hajirovic required fitness tests, but only the former was passed fit to start.
Over 3,000 Fiorentina fans are expected to be in Zurich for tonight’s match.
The last time they crossed paths was controversial, as Grasshopper were awarded a 3-0 victory and qualification in the 1998 UEFA Cup when Salernitana fans threw fireworks on to the pitch, hitting the fourth official.
The game was played in Salerno because the Stadio Artemio Franchi was the subject of a ban.
Grasshopper: Burki; Lang, Vilotic, Grichting, Pavlovic; Salatic, Abrashi; Hajrovic, Toko, Gashi; Ngamukol
Grasshopper bench: Taini, Bauer, F Feltscher, Brahimi, Ben Khalifa, Caio, Vonlanthen
Fiorentina: Neto; Roncaglia, Gonzalo Rodriguez, Savic; Cuadrado, Borja Valero, Aquilani, Ambrosini, Pasqual; Rossi, Gomez
Fiorentina bench: Munua, Alonso, Compper, Fernandez, Joaquin, Ljajic, Yakovenko
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £11,000 to be won monthly!