Lazio have left Andre Dias, Bruno Pereirinha, Marius Stankevicius and Vinicius out of their Europa League squad.
The Biancocelesti are in Group J with Trabzonspor, Legia Warsaw and Apollon.
Lazio squad for Europa League: Marchetti, Berisha, Guerrieri; Biava, Radu, Konko, Cana, Novaretti, Cavanda, Ciani, Serpieri; Ledesma, Biglia, Onazi, Ederson, Candreva, Felipe Anderson, Hernanes, Gonzalez, Lulic, Crecco; Klose, Floccari, Perea, Keita
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £11,000 to be won monthly!