Just days after shock results, Milan and Napoli need to get back on track as they face the two Genoa clubs today.
The action starts today at 17.00 UK time (16.00 GMT) at Marassi with Fabio Liverani’s boys hosting Napoli. Can Rafa Benitez and his side shake off the stunning 1-1 draw with Sassuolo?
Milan completed another last-gasp comeback to draw 3-3 with Bologna on Wednesday night and take on similarly troubled Sampdoria in the evening kick-off.
On Sunday the early game is sure to be a fiery one, the Derby della Mole between Torino and Juventus with Angelo Ogbonna facing his former club.
The round continues with Sassuolo eager to cause another upset against Lazio and Inter continuing their march on the top spot with Cagliari.
Can Roma maintain their 100 per cent record on Sunday evening when Bologna visit the Stadio Olimpico?
Week 6 is completed on Monday night with an enticing Fiorentina-Parma, as Giuseppe Rossi faces his old Euro 2012 strike partner Antonio Cassano.