Fiorentina and Dnipro face off for top spot in their Europa League group, as Juan Cuadrado and starlet Ryder Matos lead the way.
Both sides won their opening games, so go into a rainy and freezing night in Ukraine with three points apiece. It kicks off at 20.05 UK time (19.05 GMT).
Vincenzo Montella’s men are still smarting after dropping points with late goals against both Inter and Parma, but also miss the injured Giuseppe Rossi and Mario Gomez.
The only genuine striker at his disposal is Ryder Matos, who starts with support from Mati Fernandez and the fit-again Cuadrado, who has recovered from a dislocated shoulder.
Josip Ilicic and Borja Valero are not even on the bench, but Massimo Ambrosini and David Pizarro bring valuable experience to the side.
Goalkeeper Norberto Neto keeps his spot despite criticism after the Parma 2-2 draw, though Montella may well have adjusted his tactics to a 3-5-2 with Pizarro as a deep-lying playmaker.
Dnipro beat Napoli last season in the Europa League and their Coach is former Real Madrid and Tottenham boss Juande Ramos.
Their star players are Evgen Konoplyanka on the left, Brazilian midfielder Giuliano, captain Ruslan Rotan and ex-Blackburn striker Nikola Kalinic.
Dnipro can also count on Ondrej Mazuch, the Czech defender who made just two senior appearances for Fiorentina from 2007 to 2010.
Dnipro: Boyko; Mandzyuk, Mazuch, Cheberyachko, Strinic; Fedetskiy, Rotan, Kankava, Konoplyanka; Seleznyov, Zozulya
Dnipro bench: Lastuvka, Douglas, Kobakhidze, Bruno Gama, Shakhov, Politylo, Matheus
Fiorentina: Neto; Roncaglia, Compper, Rodriguez; Pizarro; Cuadrado, Ambrosini, Bakic, Alonso; Mati Fernandez, Matos
Fiorentina bench: Munua, Madrigali, Savic, Tomovic, Gulin, Ilicic, Joaquin