Milan rely on Mario Balotelli and Kaka for their Champions League crunch match at Celtic Park tonight.
It kicks off in Glasgow at 19.45 GMT with the Rossoneri on five points, Ajax four and Celtic three, so the pressure is on the Scots to win.
Massimiliano Allegri’s men are in dire form and without a win in over a month in all competition, while on Saturday Balotelli saw a penalty saved for the second time this season.
Philippe Mexes is out with an eye infection, joining Sulley Muntari, Marco Amelia, Cristian Zaccardo, Mattia De Sciglio, Giampaolo Pazzini and Stephan El Shaarawy on the treatment table.
It means Daniele Bonera plays, having made only his first appearance of the season in a 1-1 draw with Genoa on Saturday.
Valter Birsa joins Kaka in a Christmas Tree formation behind Balotelli.
Milan’s last victory in Scotland was in 1969, followed by two draws and two defeats, and are also without an away win in all competition this term.
Celtic are very strong on home turf, losing just twice in the Champions League group phase along with five draws and 16 successes.
The Hoops are still without the suspended Scott Brown and Nir Baton, while Adam Matthews and Steven Mouyokolo are injured.
Samaras is the lone striker with support from Kris Commons.
A victory in Scotland would qualify Milan for the knockouts if Ajax lose to Barcelona in tonight’s other game, but a draw would also be considered a positive result, as they go head-to-head with the Dutch giants in the final match.
Celtic: Forster, Lustig, Ambrose, Van Dijk, Izaguirre; Boerrigter, Kayal, Mulgrew, Forrest; Commons; Samaras
Celtic bench: Zaluska, Fisher, Ledley, Rogic, Stokes, Balde, Pukki
Milan: Abbiati; Abate, Zapata, Bonera, Emanuelson; Montolivo, De Jong, Poli; Birsa, Kaka; Balotelli
Milan bench: Coppola, Silvestre, Constant, Nocerino, Cristante, Robinho, Matri