Roma have Francesco Totti back on the bench and Adem Ljajic against his old club as Roma host Giuseppe Rossi’s Fiorentina.
The early kick-off starts at 11.30 GMT, click here for a match preview.
The Giallorossi are still unbeaten this season, but have fallen off the top of the table after four consecutive draws.
Captain Totti returns to the bench over a month on from his thigh injury, though Federico Balzaretti is still unavailable.
Ljajic left Fiorentina over the summer after refusing to sign a new contract and starts alongside Gervinho and Alessandro Florenzi.
Vincenzo Montella is back to face his old club at the Stadio Olimpico, as are Alberto Aquilani and the not 100 per cent fit David Pizarro, who is on the bench.
Manuel Pasqual has also recovered from injury, while Giuseppe Rossi aims to increase his lead at the top of the Capocannoniere charts flanked by Juan Guillermo Cuadrado and Juan Manuel Vargas.
Mario Gomez is still out with a knee injury after surgery and an inflammation.
The Tuscans are in joint fourth place and fresh from an exhilarating 4-3 victory over Hellas Verona.
Their record in Rome is not reassuring, losing 12 of their last 14 Serie A visits and not keeping a clean sheet here in 20 attempts.
Roma: De Sanctis; Maicon, Benatia, Castan, Dodò; Pjanic, De Rossi, Strootman; Florenzi, Ljajic, Gervinho
Roma bench: Skorupski, Bradley, Marquinos, Totti, Taddei, Destro, Burdisso, Jedvaj, Torosidis, Romagnoli, Borriello, Ricci
Fiorentina: Neto; Tomovic, Savic, Rodriguez, Pasqual; Aquilani, Ambrosini, Borja Valero; Cuadrado, Rossi, Vargas
Fiorentina bench: Munua, Alonso, Roncaglia, Compper, Pizarro, Rebic, Mati Fernadez, Joaquin, Wolski, Matos, Ilicic, Olivera
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's World Cup tipster competition - £10,000 to be won!