Napoli try to close on the top spots with a trip to Cagliari and Livorno host troubled Udinese, while on Sunday it’s the massive Milan Derby.
Click here for all the individual match previews from Serie A Week 17, the last before the Christmas break.
The action begins today at 17.00 GMT with Livorno-Udinese, which is fast turning into a relegation tussle, and this evening Napoli visit Cagliari.
Bologna-Genoa has Stefano Pioli hanging by a thread at 11.30 GMT on Sunday, followed by leaders Juventus travelling to Atalanta, Roma hosting Catania, Fiorentina at the temperamental Sassuolo and Lazio visiting Hellas Verona.
Sampdoria-Parma and Torino-Chievo are intriguing ties between sides on good form.
The final Serie A game of 2013 is a big one indeed: The Derby della Madonnina between arch rivals Inter and Milan.