Roma welcome bottom of the table Catania with Francesco Totti back in the starting XI after two months and a new system.
It kicks off at the Stadio Olimpico at 14.00 GMT, click here for a match preview.
The Giallorossi are still unbeaten under Coach Rudi Garcia and need a victory to keep up with leaders Juventus ahead of their January 5 head-to-head.
Captain Totti returned as a substitute in the 2-2 draw with Milan last week, but this is his first start since October 18.
He is flanked by Gervinho and Adem Ljajic in support of centre-forward Mattia Destro in a new 4-2-3-1 system, while Marco Borriello and Federico Balzaretti are injured.
There have to be big changes in midfield, where Daniele De Rossi and Kevin Strootman are suspended, but Miralem Pjanic returns from his ban.
Their momentum has slowed recently, notching up five draws and a win in the last six rounds.
Catania are bottom of the table and have lost their last eight consecutive away games, so on paper this will be a whitewash.
Nicolas Spolli is suspended in defence, while Sergio Almiron and Giuseppe Bellusci also miss out.
Roma: De Sanctis; Maicon, Benatia, Castan, Dodò; Bradley, Pjanic; Ljajic, Totti, Gervinho; Destro
Catania: Frison; Peruzzi, Legrottaglie, Rolin, Alvarez; Izco, Guarente, Plasil; Barrientos, Leto, Castro