Napoli try to get back into the Scudetto race against plucky Chievo and leaders Juventus visit a revived Lazio today.
It all begins at 17.00 GMT when Rafa Benitez’s Napoli aim to put their surprise 2-2 draw with Bologna behind them against giant-killers Chievo, potentially with Jorginho’s debut.
Juventus target a 13th consecutive Serie A victory, but must get past a Lazio side completely revitalised under Edy Reja.
It’s also their second visit to the Stadio Olimpico this week, having lost the Coppa Italia quarter-final to Roma on Tuesday.
Tomorrow the early kick-off is an intriguing Verona-Roma with Luca Toni facing his former teammates.
Clarence Seedorf’s Milan travel to Cagliari, while Inter hope to end their crisis against bottom of the table Catania.
Livorno-Sassuolo and Sampdoria-Bologna are relegation tussles, but Parma can send Udinese further down the slippery slope.
Torino hope to continue their remarkable campaign when hosting bad travellers Atalanta.
The evening kick-off sees fourth-placed Fiorentina take on Alberto Gilardino’s Genoa, who are fresh from beating Inter.
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £11,000 to be won monthly!