Fiorentina give former Manchester United midfielder Anderson his first start against Cagliari this afternoon.
It kicks off at 17.00 GMT at the Stadio Sant’Elia, click here for a match preview.
Once again, only a maximum of 5,000 fans are allowed into the stands due to restructuring work and safety concerns.
Fiorentina wasted the opportunity to close the gap on third-place Napoli to one point last weekend, as they were held to a thrilling 3-3 draw by Genoa.
Vincenzo Montella goes to Sardinia without the injured Mario Gomez, Giuseppe Rossi, Massimo Ambrosini and Nenad Tomovic.
Former Manchester United midfielder Anderson therefore gets his first start, having debuted briefly against Genoa.
Alessandro Matri leads the attack with support from Josip Ilicic, but Juan Cuadrado is initially rested with the not 100 per cent fit Borja Valero.
Modibo Diakite is also on the bench just hours after his loan from Sunderland.
Cagliari were downbeat after leading Milan last week only to lose 2-1 with last-gasp goals from Mario Balotelli and Giampaolo Pazzini.
The Sardinians have Andrea Cossu suspended, while Victor Ibarbo is in hospital with appendicitis.
Marco Sau therefore starts with Mauricio Pinilla. Matias Vecino could make his Cagliari debut against his former club just two days after completing the loan move from Fiorentina.
Cagliari: Avramov; Perico, Rossettini, Astori, Murru; Ekdal, Conti, Dessenal; Cabrera, Sau; Pinilla
Cagliari bench: Silvestri, Ibraimi, Eriksson, Adryan, Vecino, Del Fabro
Fiorentina: Neto; Roncaglia, Rodriguez, Savic, Vargas; Pizarro, Aquilani, Mati Fernandez; Anderson, Ilicic; Matri
Fiorentina bench: Lupatelli, Rosati, Diakite, Compper, Bakic, Cuadrado, Joaquin, Borja, Pasqual, Wolski, Matos
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £11,000 to be won monthly!