Napoli are forced to reshuffle for their trip to Sassuolo, missing Jorginho, Gokhan Inler and Jose Callejon.
It kicks off at the Mapei Stadium on Sunday at 14.00 GMT, click here for a match preview.
Inler, Jorginho and Callejon are all ruled out by a one-match ban, while Giandomenico Mesto and Juan Camilo Zuniga are still injured.
New signing Henrique is ready for his Serie A debut, as the international transfer came through from Palmeiras and he played briefly in the Coppa Italia semi-final against Roma on Wednesday.
Napoli squad for Sassuolo: Reina, Rafael, Colombo, Contini, Albiol, Britos, Henrique, Fernandez, Ghoulam, Maggio, Reveillere, Behrami, Dzemaili, Radosevic, Insigne, Mertens, Hamsik, Pandev, Higuain, Duvan Zapata