All eyes are on Napoli-Juventus tonight, but Roma can take advantage in the early trip to Sassuolo and Inter play on Monday.
Remember the clocks went forward an hour in Europe last night, so all kick-off times now listed are GMT+1.
It all begins at 11.30 UK time (10.30 GMT) when Roma visit Sassuolo, a side that held them to a surprise 1-1 draw at the Olimpico earlier this season.
At 14.00 UK time (13.00 GMT), Lazio-Parma is a battle for European places, Verona try to put their crisis behind them against Genoa, Sinisa Mihajlovic and Vincenzo Montella face their pasts in Sampdoria-Fiorentina, while Torino host Cagliari.
Tonight there’s a huge battle with third against first, as Juventus visit the Stadio San Paolo without Carlos Tevez against Napoli.
Week 31 stretches on into Monday with Udinese-Catania at 18.00 UK time (17.00 GMT) and Livorno-Inter at 20.00 UK time (19.00 GMT).