Udinese are without Antonio Di Natale, Maicosuel, Maurizio Domizzi and Gianpiero Pinzi against Fiorentina.
This Serie A clash kicks off on Sunday at 14.00 UK time (13.00 GMT), click here for a match preview.
Francesco Guidolin is forced to reshuffle with several stars missing the trip to Florence.
These include Di Natale and Maicosuel in attack, Domizzi in defence and Pinzi for the midfield.
It leaves only three forwards available: Luis Muriel, Nico Lopez and Piotr Zielinski.
Udinese squad for Fiorentina: Brkic, Kelava, Scuffet; Basta, Bubnjic, Danilo, Gabriel Silva, Heurtaux, Naldo, Widmer; Allan, Badu, Fernandes, Jadson, Yebda, Lazzari, Pereyra; Muriel, Nico Lopez, Zielinski