Sampdoria are without Manolo Gabbiadini and Gaetano Berardi against Inter on Sunday, but Maxi Lopez faces Mauro Icardi.
It kicks off tomorrow at 14.00 UK time (13.00 GMT), click here for a match preview.
Gabbiadini is out after damaging his shoulder, while Berardi has also failed to shake off a knock in time.
Sinisa Mihajlovic, who sits out a touchline ban tomorrow, has called up youth team player Mattia Lombardo.
Captain Daniele Gastaldello is back in the squad after missing last week’s 2-0 defeat to Lazio.
It is a very special occasion for Maxi Lopez, who’ll get the chance to face Mauro Icardi.
The men were teammates at Sampdoria and best friends, until Lopez’s wife Wanda Nara left him to move in with Inter striker Icardi.
Sampdoria squad for Inter: Da Costa, Falcone, Fiorillo; Costa, De Silvestri, Fornasier, Gastaldello, Mustafi, Regini, Rodriguez, Salamon; Bjarnason, Krsticic, Lombardo, Obiang, Palombo, Renan, Sestu, Soriano, Wszolek; Eder, Maxi Lopez, Okaka, Sansone