Napoli visit Udinese this afternoon, but are without Gonzalo Higuain and Dries Mertens.
It kicks off at the Stadio Friuli at 14.00 UK time (13.00 GMT), click here for a match preview.
Rafa Benitez completely revamps his side yet again, though this time many of the decisions are forced upon him.
Higuain is out injured after picking up a knock in training, joining Christian Maggio, Miguel Angel Britos and Rafael on the sidelines.
Juan Camilo Zuniga is called up to the squad, but it’s not clear whether he is ready to make his comeback.
Mertens scored a sensational goal last week, but he sits out a ban in Udine, so Lorenzo Insigne and Duvan Zapata start.
Marek Hamsik and Jose Callejon also return to the starting XI with Anthony Reveillere at right-back and Paulo Henrique moved to central defence for Raul Albiol.
Udinese are comfortably mid-table and can play without pressure, but native Neapolitan Antonio Di Natale is surprisingly only on the bench.
Instead Luis Muriel leads the attack with support from Bruno Fernandes and Roberto Pereyra.
Andrea Lazzari is still out of action for the Friulani, but Giampiero Pinzi returns.
Udinese: Scuffet; Heurtaux, Danilo, Domizzi, Gabriel Silva; Pinzi, Badu, Allan; Fernandes, Pereyra; Muriel
Napoli: Reina; Reveillere, Fernandez, Henrique, Ghoulam; Behrami, Inler; Insigne, Hamsik, Callejon; Duvan Zapata