Fiorentina try to get over their Coppa Italia Final defeat with Giuseppe Rossi ready to come on against desperate Sassuolo.
It kicks off at 18.00 UK time (17.00 GMT), click here for a match preview.
This Serie A fixture was postponed until today because the Viola had to play Napoli in the Coppa Italia Final on Saturday night, losing 3-1.
They are still sure of a place in the Europa League and want to consolidate fourth position in the table.
Juan Cuadrado was suspended for that Final in Rome, so he returns to the starting XI with Alessandro Matri and Rafal Wolski.
Rossi made his comeback on Saturday four months after knee ligament damage and is expected to make his Serie A return this evening too.
Mario Gomez and Ante Rebic are still out of action, joined by goalkeeper Norberto Neto – who fractured his finger – and defender Marvin Compper.
It means Antonio Rosati has a rare start in goal for Fiorentina.
Sassuolo are in the thick of the relegation dogfight, which is extremely tight as even Catania and Livorno aren’t sure of going down now.
They have shown signs of improvement recently and can count on starlet Domenico Berardi, striker Simone Zaza and ex-Bayern Munich youth team player Nicola Sansone.
The absentee list includes Thomas Manfredini, Marius Alexe, Francesco Acerbi and the suspended Francesco Magnanelli.
Fiorentina: Rosati; Diakitè, Savic, Rodriguez, Pasqual; Mati Fernandez, Pizarro, Borja Valero; Cuadrado, Matri, Wolski
Fiorentina bench: Lupatelli, Vargas, Tomovic, Roncaglia, Hegazi, Aquilani, Anderson, Ambrosini, Ilicic, Joaquin, Rossi, Matos
Sassuolo: Pegolo; Gazzola, Antei, Cannavaro, Longhi; Chibsah, Missiroli, Biondini; Berardi, Zaza, Sansone
Sassuolo bench: Pomini, Polito, Ariaudo, Mendes, Terranova, Rosi, Ziegler, Brighi, Marrone, Masucci, Floro Flores, Floccari
Tickets for the Champions League final between Juventus and Real Madrid are still on sale with reseller Viagogo - Click to find out more