Christian Maggio makes his comeback after three months as a revamped Napoli visit Sampdoria.
It kicks off at 14.00 UK time (13.00 GMT), click here for a match preview.
Neither side has anything to play for but pride at Marassi, though the home fans will be pleading Coach Sinisa Mihajlovic to stay on.
Stefano Okaka is suspended, Pedro Obiang and Gaetano Berardi sidelined, so Maxi Lopez leads the attack with Roberto Soriano, Eder and Manolo Gabbiadini.
Napoli make numerous changes after securing their Champions League play-off spot, above all welcoming back Maggio for his first appearance since undergoing emergency surgery on a collapsed lung in February.
Miguel Angel Britos and Blerim Dzemaili sit out bans, while Gonzalo Higuain, Raul Albiol, Rafael and Valon Behrami are injured.
It’s therefore a whole new attack with Duvan Zapata supported by Lorenzo Insigne, Marek Hamsik and Jose Callejon.
Sampdoria: Fiorillo; De Silvestri, Mustafi, Gastaldello, Regini; Palombo, Krsticic; Gabbiadini, Soriano, Eder; Maxi Lopez
Napoli: Reina; Maggio, Fernandez, Mesto, Reveillere; Inler, Jorginho; Insigne, Hamsik, Callejon; Duvan Zapata
Check out OLBG.com's list of ££ Free Bets from UK bookmakers before placing your bets!