Gonzalo Higuain, Marek Hamsik and Lorenzo Insigne start in Napoli’s Champions League play-off with Athletic Bilbao.
The first leg kicks off tonight at 19.45 UK time (18.45 GMT) at the Stadio San Paolo with the decider at the San Mames next week.
Rafael is back in goal after a lengthy injury lay-off and can celebrate his Brazil call-up too.
Higuain is able to start despite a late return from World Cup duty, supported by Hamsik, Insigne and Jose Callejon.
There is a surprise at the back, where Miguel Angel Britos partners new signing Kalidou Koulibaly, while Walter Gargano is also an unexpected pick ahead of Gokhan Inler.
Athletic Bilbao finished fourth in La Liga last season under Marcelo Bielsa, but Ernesto Valverde took over this term.
Ander Herrera has been sold to Manchester United for €36m, but striker Aritz Aduriz is still leading the way.
Iker Muniain is a particular danger for Napoli down the flank.
There will be relatively few Athletic fans at the San Paolo, as this game coincides with the Semana Grande de Bilbao festival.
Napoli: Rafael; Maggio, Albiol, Koulibaly, Britos; Gargano, Jorginho; Callejon, Hamsik, Insigne; Higuain
Napoli bench: Andujar, Mesto, Ghoulam, Inler, Mertens, Michu, Zapata
Athletic Bilbao: Iraizoz; De Marcos, Gurpegi, Laporte, Balenziaga; Iturraspe, Mikel Rico; Susaeta, Benat, Muniain; Aduriz
Athletic Bilbao bench: Iago, San Jose, Iraola, Guillermo Fernandez, Erik Moran, Unai Lopez, Ibai Gomez
Ref: Eriksson (SWE)