Juventus start Carlos Tevez, Alvaro Morata and Arturo Vidal in the Champions League with Borussia Dortmund.
It kicks off in Turin at 19.45 GMT and is the first leg in the Round of 16.
Follow all the action as it happens on our LIVEBLOG, even for mobile users.
The Bianconeri have always struggled to match their Serie A success in Europe and last season went out in the group stage to Galatasaray.
Juventus start Carlos Tevez, Alvaro Morata and Arturo Vidal in the Champions League with Borussia Dortmund.
It kicks off in Turin at 19.45 GMT and is the first leg in the Round of 16.
Follow all the action as it happens on our LIVEBLOG, even for mobile users.
The Bianconeri have always struggled to match their Serie A success in Europe and last season went out in the group stage to Galatasaray.
Vidal missed Friday’s 2-1 win over Atalanta due to a muscular problem, but the Chilean is back in the starting XI this evening with Andrea Pirlo and Paul Pogba.
Morata gets the nod in attack alongside ‘Apache’ Tevez.
Borussia Dortmund ended 2014 bottom of the Bundesliga, but have since rediscovered their form with three consecutive victories.
Even during their worst domestic period, BVB were still hugely impressive in the Champions League and comfortably won their group.
Ciro Immobile is the surprise pick to start in attack against his former club, though the ex-Torino Capocannoniere pointed out this week he never really played for the Bianconeri and felt closer to their arch-rivals.
Marco Reus is still finding his form after a long injury lay-off, while ex-Genoa defender Sokratis Papasthatopoulos is picked ahead of Neven Subotic.
Pierre-Emerick Aubameyang’s extraordinary pace could cause serious problems for an ageing Juve back four.
Juve’s unbeaten home run in all competition now stands at 38 wins and eight draws.
Borussia Dortmund have faced Juventus seven times and never managed to keep a clean sheet.
Juventus: Buffon; Lichtsteiner, Bonucci, Chiellini, Evra; Marchisio, Pirlo, Pogba; Vidal; Tevez, Morata
Juventus bench: Storari, Caceres, Ogbonna, Padoin, Pereyra, Coman, Llorente
Borussia Dortmund: Weidenfeller; Piszczek, Papasthatopoulos, Hummels, Schmelzer, Gündogan, Sahin, Mkhitaryan, Reus, Aubameyang, Immobile
Borussia Dortmund bench: Langerak, Ginter, Kirch, Kagawa, Kuba, Kehl, Ramos