Napoli aim to continue their Europa League march and welcome impressive Dinamo Moscow to the San Paolo.
The first leg in this Round of 16 tie kicks off at 20.05 GMT.
Rafa Benitez has great history in this competition and his side set a new record by keeping five consecutive clean sheets.
The Partenopei are unbeaten in 10 European home fixtures, winning eight of them.
However, Dinamo Moscow are tricky opponents, starting out from the third preliminary round and remaining unbeaten the whole way with nine wins and three draws.
Napoli aim to continue their Europa League march and welcome impressive Dinamo Moscow to the San Paolo.
The first leg in this Round of 16 tie kicks off at 20.05 GMT.
Rafa Benitez has great history in this competition and his side set a new record by keeping five consecutive clean sheets.
The Partenopei are unbeaten in 10 European home fixtures, winning eight of them.
However, Dinamo Moscow are tricky opponents, starting out from the third preliminary round and remaining unbeaten the whole way with nine wins and three draws.
They won all six matches in the group phase and knocked Anderlecht out in the Round of 32.
Midfielder Artur Yusupov is suspended for the visitors, having previously played seven games and scored once, while Napoli are without Manolo Gabbiadini and Lorenzo Insigne, but Miguel Angel Britos shook off a problem to start.
Marek Hamsik is dropped in favour of Jonathan de Guzman, Jose Callejon and Dries Mertens behind Gonzalo Higuain.
Benitez confirmed he has no faith in goalkeeper Rafael, choosing Mariano Andujar for both Serie A and Europa League games.
The game is officiated by Greek referee Tasos Sidiropoulos.
Napoli: Andujar; Henrique, Koulibaly, Britos, Ghoulam; Jorginho, Inler; Callejon, De Guzman, Mertens; Higuain
Napoli bench: Rafael, Zuniga, Albiol, Mesto, Hamsik, David Lopez, Duvan Zapata
Dinamo Moscow: Gabulov; Kozlov, Hubocan, Samba, Zhirkov; Valbuena, Zobnin, Vainqueur, Dzsudzsak; Kuranyi, Kokorin
Dinamo bench: Shunin, Buttner, Douglas, Rotenberg, Ionov, Katrich, Tashaev