Napoli start Gonzalo Higuain and Lorenzo Insigne against Jackson Martinez’s Porto in the Europa League.

The first leg of the Round of 16 tie kicks off in Oporto at 18.00 GMT.

Napoli start Gonzalo Higuain and Lorenzo Insigne against Jackson Martinez’s Porto in the Europa League.

The first leg of the Round of 16 tie kicks off in Oporto at 18.00 GMT.

Jorginho is not on the UEFA list, while Juan Camilo Zuniga and Giandomenico Mesto are long-term injury cases.

Christian Maggio also misses out after picking up a knock in training this week, so Anthony Reveillere starts at right-back.

Higuain leads the attack with Marek Hamsik, Jose Callejon and Insigne, while Dries Mertens, Federico Fernandez and Gokhan Inler are rested for this game.

Valon Behrami is able to start after he was ruled out of Sunday’s win over Roma, but the surprise choice in midfield is January signing Paulo Henrique.

Porto surprisingly sacked Coach Paulo Fonseca on March 5 after failing to win in four competitive matches, promoting B-team manager Luis Castro to the main job.

Jackson Martinez is the star striker who had been heavily linked with Napoli over the summer and he is supported by ex-Inter winger Ricardo Quaresma.

The only other time these teams met was in the 1974-75 UEFA Cup, when the Partenopei won 1-0 home and away.

Porto: Helton; Danilo, Maicon, Mangala, Alex Sandro; Fernando; Quaresma, Defour, Carlos Eduardo, Varela; Martinez

Porto bench: Fabiano, Reyes, Herrera, Lica, Quintero, Ghilas, Ricardo

Napoli: Reina; Reveillere, Albiol, Britos, Ghoulam; Henrique, Behrami; Callejon, Hamsik, Insigne; Higuain

Napoli bench: Colombo, Fernandez, Dzemaili, Inler, Mertens, Pandev, Zapata

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