Follow the build-up and action from all seven Serie A evening games, including Fiorentina v Milan, Napoli at Sassuolo, Inter host Atalanta and Palermo-Genoa.
They kick off at 19.45 UK time (18.45 GMT) and we’ll bring you line-ups, goals and incidents as they happen.
If you are on a mobile device or tablet, then follow our LIVEBLOG HERE.
Sinisa Mihajlovic’s revamped Milan face a stern test straight away at Fiorentina, where Paulo Sousa makes his Serie A debut.
Inter have transformed their squad and could start Stevan Jovetic in the Lombardy Derby with Atalanta at San Siro.
Napoli are under new management, so how will Maurizio Sarri’s side fare away to Domenico Berardi’s Sassuolo?
Palermo v Genoa promises fireworks, Empoli-Chievo has question marks and history is made as Frosinone and Carpi make their all-time top flight debuts against Torino and Sampdoria respectively.