Pescara recovered from their Week 1 mauling to beat Perugia 2-1 in Serie B.
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The Delfini needed a boost after opening the season with a 4-0 demolition at the hands of Livorno.
Ledian Memushaj converted a penalty and Gianluca Caprari scored within a minute of coming off the bench to secure victory.
Samuel Di Carmine struck late on with a left-foot scorcher, but it was too late to complete a comeback.
Pescara 2-1 Perugia
Scorers: Memushaj pen 30 (Pes), Caprari 76 (Pes), Di Carmine 91 (Per)