Milan go for all-out attack as they host second-placed Palermo in what could be an upset at San Siro.
It kicks off at 19.45 UK time (18.45 GMT), follow the action as it happens on our LIVEBLOG.
The Rossoneri are struggling with two defeats in the first three rounds, including last week’s 1-0 to arch rivals Inter.
Sinisa Mihajlovic insists he saw improvements in that performance and sticks with the same starting XI.
That means Riccardo Montolivo, Jack Bonaventura and Juraj Kucka in midfield, plus Keisuke Honda supporting strikers Luiz Adriano and Carlos Bacca.
It’s safe to assume Mario Balotelli will play a part in this match, having impressed when coming off the bench against Inter for his ‘debut.’
Andrea Bertolacci, Jeremy Menez, M’Baye Niang, Luca Antonelli and Philippe Mexes are all unavailable.
If Milan are stuttering, then Palermo are on a roll and remain unbeaten, sitting pretty in second place on a par with Roma.
Their 100 per cent record was ended last week in a thrilling 2-2 draw with newly-promoted Carpi.
Franco Vazquez is still making magic, aided by Sweden Under-21 international stars Oscar Hiljemark and Robin Quaison.
Alberto Gilardino is on the bench against his former club in a stadium that never really warmed to him, as youngster Djurdjevic is picked instead.
Francesco Bolzoni and Michel Morganella are the only injury absentees for Coach Beppe Iachini, while Aljaz Struna returns from suspension.
Milan: Diego Lopez; Abate, Zapata, Romagnoli, De Sciglio; Kucka, Montolivo, Bonaventura; Honda; Luiz Adriano, Bacca
Milan bench: Abbiati, Donnarumma, Mauri, Suso, Cerci, Ely, Poli, Nocerino, Alex, De Jong, Balotelli, Calabria
Palermo: Sorrentino; Struna, Gonzalez, El Kaoutari, Lazaar; Hiljemark, Jajalo, Chochev; Vazquez; Quaison, Djurdjevic
Palermo bench: Colombi, Vitiello, Rispoli, Andelkovic, Goldaniga, Trajkovski, Cassini, Gilardino, Brugman, Maresca, Rigoni, Daprelà