Edin Dzeko, Lucas Digne and Alessandro Florenzi are back, but Roma miss Daniele De Rossi against Sampdoria.
It kicks off on Sunday at 19.45 GMT, click here for a match preview.
Luciano Spalletti is seeking a third consecutive Serie A victory after beating Frosinone and Sassuolo.
While Dzeko, Digne and Florenzi return from injury lay-offs, De Rossi and Vasilis Torosidis are ruled out.
Edin Dzeko, Lucas Digne and Alessandro Florenzi are back, but Roma miss Daniele De Rossi against Sampdoria.
It kicks off on Sunday at 19.45 GMT, click here for a match preview.
Luciano Spalletti is seeking a third consecutive Serie A victory after beating Frosinone and Sassuolo.
While Dzeko, Digne and Florenzi return from injury lay-offs, De Rossi and Vasilis Torosidis are ruled out.
Norbert Gyomber is also absent after Spalletti revealed he finished the game on Tuesday night with a fractured toe.
“De Rossi hung Gyomber’s picture in the locker room as an example of the attitude you need to keep going.”
Roma squad for Sampdoria: Lobont, Szczesny, De Sanctis; Rudiger, Digne, Castan, Maicon, Emerson Palmieri, Manolas, Zukanovic, Nura; Perotti, Iago Falque, Pjanic, Keita, Vainqueur, Florenzi, Uçan; Dzeko, Totti, Salah, El Shaarawy, Sadiq