Keisuke Honda, Juraj Kucka and Alex are out of Milan’s trip to Atalanta on Sunday afternoon.
It kicks off at 14.00 UK time (13.00 GMT), click here for a match preview.
Honda returned from international duty in Japan with a knock and failed a fitness test during today’s training session.
Defender Alex also misses out along with Kucka and M’Baye Niang.
It is reported Mattia De Sciglio could be used in Honda’s position wide right of a four-man midfield.
Milan squad for Atalanta: Abbiati, Donnarumma, Diego Lopez; Abate, Antonelli, Calabria, De Sciglio, Ely, Romagnoli, Simic, Zapata; Bertolacci, Bonaventura, Jose Mauri, Locatelli, Montolivo, Poli; Bacca, Balotelli, Boateng, Luiz Adriano, Menez