High-flying Chievo face a potentially dangerous trip to Pescara, were even the biggest clubs have so far struggled.
It kicks off at 17.00 UK time (16.00 GMT), you can follow the action as it happens on the LIVEBLOG.
The Flying Donkeys have had a remarkable campaign so far and are sitting pretty in joint fourth place with Roma, Lazio, Milan and another surprise outfit, Bologna.
They visit a Pescara side that had taken the lead here against both Napoli and Inter, only to be pegged back 2-2 and lose 2-1 at the last minute respectively.
Chievo saw their strong run end with last week’s defeat at Napoli and lost Fabrizio Cacciatore to injury.
Valter Birsa pulls the strings behind Antonio Floro Flores and Roberto Inglese in attack.
Pescara’s last two outings have been eventful, as they twice drew against a side playing with nine men.
Francesco Zampano begins a two-match ban after he was caught on camera clearing a shot off the line with his hand, so Alessandro Crescenzi takes his place.
Also absent are Jean-Christophe Bahebeck, Norbert Gyomber and Simone Pepe.
Rey Manaj is chosen to lead the attack with Gianluca Caprari and Ahmed Benali, while Valerio Verre is a key figure in midfield.
These teams have met only twice before in Serie A and Chievo won both of them 2-0, all four goals coming in the final 15 minutes.
Pescara: Bizzarri; Crescenzi, Campagnaro, Fornasier, Biraghi; Verre, Brugman, Memushaj; Benali, Caprari; Manaj
Pescara bench: Fiorillo, Bruno, Cristante, Zuparic, Aquilani, Vitturini, Mitrita, Muric, Coda
Chievo: Sorrentino; Frey, Dainelli, Spolli, Gobbi; Castro, Radovanovic, Hetemaj; Birsa; Inglese, Floro Flores
Chievo bench: Seculin, Confente, De Guzman, Rigoni, Gamberini, Cesar, Izco, Sardo, Parigini, Pellissier, Costa, Meggiorini