Fiorentina pair Nikola Kalinic with Khouma Babacar in a tricky Europa League trip to Slovan Liberec.
It kicks off at 18.00 UK time (17.00 GMT), follow the action from all four Italian Europa League sides in the LIVEBLOG.
The Viola are still unbeaten in the tournament so far, drawing 0-0 away to PAOK Salonika and crushing 10-man Qarabag 5-1.
Their Serie A form, however, has been poor with
Fiorentina pair Nikola Kalinic with Khouma Babacar in a tricky Europa League trip to Slovan Liberec.
It kicks off at 18.00 UK time (17.00 GMT), follow the action from all four Italian Europa League sides in the LIVEBLOG.
The Viola are still unbeaten in the tournament so far, drawing 0-0 away to PAOK Salonika and crushing 10-man Qarabag 5-1.
Their Serie A form, however, has been poor with a particular struggle to score goals, despite Coach Paulo Sousa favouring an attack-minded approach.
Liberec, on the other hand, have scored in the opening minute of both their Europa League matches this term, so the Tuscans are going to need to be on their toes from the get-go.
Despite that, Slovan only have one point and have looked wobbly in defence.
Kalinic again starts alongside Babacar, but Federico Bernardeschi is benched.
Josip Ilicic is still recovering from an ankle injury sustained on international duty.
Fiorentina are unbeaten in five meetings with Czech clubs, but Slovan Liberec are yet to lose in two home games with Italian opposition.
Slovan Liberec: Dubravka; Coufal, Hovorka, Karafiat, Sykora; Breite, Folprecht; Navratil, Sevcik, Vuch; Komilichenko
Fiorentina: Tatarusanu, Tomovic, Gonzalo Rodriguez, Astori; Cristoforo, Badelj, Vecino, Borja Valero, Maxi Olivera; Kalinic, Babacar