Inter are without Gabriel Barbosa, Geoffrey Kondogbia, Gary Medel and Stevan Jovetic for their trip to Sampdoria.
It kicks off on Sunday at 19.45 GMT, click here for a match preview.
Coach Frank de Boer had hinted in his Press conference that although Kondogbia’s injury was “not serious,” he wasn’t yet fit to take part in tomorrow’s game.
Gabigol and Jovetic also miss out through injury, while Medel continues his three-match ban.
It's rumoured Gabriel Barbosa is not injured so, despite scoring in two friendlies, he is not even considered for the bench by De Boer.
There is a comeback for Jonathan Biabiany.
Inter squad for Sampdoria: Handanovic, Carrizo, Berni; Andreolli, Ranocchia, Ansaldi, Santon, Murillo, Miranda, D'Ambrosio, Nagatomo, Miangue; Joao Mario, Banega, Gnoukouri, Brozovic; Palacio, Icardi, Biabiany, Eder, Perisic, Candreva