Both Cagliari and Roma are in dire need of a boost going into the Stadio Sant’Elia.
Crotone’s home form was crucial in securing their first ever promotion to Serie A, but they’ll be ‘hosting’ Genoa at Pescara’s Stadio Adriatico.
The pressure is already piling on Frank de Boer after an embarrassing 2-0 reverse at Chievo, but this is a fixture Inter have never lost.
An experienced Juventus side visits the youthful exuberance of Lazio in an intriguing clash after both teams won the opening round.
Napoli look to bounce-back and Milan look to consolidate as the pair meet at San Paolo.